4,304 research outputs found

    Distributed model predictive control of linear systems with persistent disturbances

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    This article presents a new form of robust distributed model predictive control (MPC) for multiple dynamically decoupled subsystems, in which distributed control agents exchange plans to achieve satisfaction of coupling constraints. The new method offers greater flexibility in communications than existing robust methods, and relaxes restrictions on the order in which distributed computations are performed. The local controllers use the concept of tube MPC – in which an optimisation designs a tube for the system to follow rather than a trajectory – to achieve robust feasibility and stability despite the presence of persistent, bounded disturbances. A methodical exploration of the trades between performance and communication is provided by numerical simulations of an example scenario. It is shown that at low levels of inter-agent communication, distributed MPC can obtain a lower closed-loop cost than that obtained by a centralised implementation. A further example shows that the flexibility in communications means the new algorithm has a relatively low susceptibility to the adverse effects of delays in computation and communication

    Brain activation during face perception: evidence of a developmental change.

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    Behavioral studies suggest that children under age 10 process faces using a piecemeal strategy based on individual distinctive facial features, whereas older children use a configural strategy based on the spatial relations among the face's features. The purpose of this study was to determine whether activation of the fusiform gyrus, which is involved in face processing in adults, is greater during face processing in older children (12-14 years) than in younger children (8-10 years). Functional MRI scans were obtained while children viewed faces and houses. A developmental change was observed: Older children, but not younger children, showed significantly more activation in bilateral fusiform gyri for faces than for houses. Activation in the fusiform gyrus correlated significantly with age and with a behavioral measure of configural face processing. Regions believed to be involved in processing basic facial features were activated in both younger and older children. Some evidence was also observed for greater activation for houses versus faces for the older children than for the younger children, suggesting that processing of these two stimulus types becomes more differentiated as children age. The current results provide biological insight into changes in visual processing of faces that occur with normal development

    Exploring exogenous controls on short- versus long-term erosion rates globally

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    Erosion is directly tied to landscape evolution through the relationship between sediment flux and vertical lowering of the land surface. Therefore, the analysis of erosion rates across the planet measured over different temporal domains may provide perspectives on the drivers and processes of land surface change over various timescales. Different metrics are commonly used to quantify erosion (or denudation) over timescales of <101 years (suspended sediment flux) and 103–106 years (cosmogenic radionuclides), meaning that reconciling potentially contrasting rates at these timescales at any location is challenging. Studies over the last several decades into erosion rates and their controls have yielded valuable insights into geomorphic processes and landforms over time and space, but many are focused at local or regional scales. Gaps remain in understanding large-scale patterns and exogenous drivers (climatic, anthropogenic, tectonic) of erosion across the globe. Here we leverage the expanding availability and coverage of cosmogenic-derived erosion data and historical archives of suspended sediment yield to explore these controls more broadly and place them in the context of classical geomorphic theory. We make the following findings in this paper: (1) there are relationships between both long- and short-term erosion rates and mean annual precipitation, as well as aridity, similar to that proposed in classic geomorphic literature on erosion; (2) agricultural activities have apparently increased short-term erosion rates, outpacing natural drivers; (3) short-term erosion rates exceed long-term rates in all climatic regions except in mid- and high latitudes, where long-terms rates are higher due to the influence of repeated glacial cycles; and (4) tectonically active margins have generally higher long-term erosion rates and apparently lower rainfall thresholds for erosion which potentially arise due to steeper slopes and associated landslides, overcoming vegetative root reinforcement. These results highlight the complex interplay of external controls on land surface processes and reinforce the view that timescale of observation may reveal different erosion rates and principal controls

    Differential spatial repositioning of activated genes in Biomphalaria glabrata snails infected with Schistosoma mansoni

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    Copyright @ 2014 Arican-Goktas et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.This article has been made available through the Brunel Open Access Publishing Fund.Schistosomiasis is an infectious disease infecting mammals as the definitive host and fresh water snails as the intermediate host. Understanding the molecular and biochemical relationship between the causative schistosome parasite and its hosts will be key to understanding and ultimately treating and/or eradicating the disease. There is increasing evidence that pathogens that have co-evolved with their hosts can manipulate their hosts' behaviour at various levels to augment an infection. Bacteria, for example, can induce beneficial chromatin remodelling of the host genome. We have previously shown in vitro that Biomphalaria glabrata embryonic cells co-cultured with schistosome miracidia display genes changing their nuclear location and becoming up-regulated. This also happens in vivo in live intact snails, where early exposure to miracidia also elicits non-random repositioning of genes. We reveal differences in the nuclear repositioning between the response of parasite susceptible snails as compared to resistant snails and with normal or live, attenuated parasites. Interestingly, the stress response gene heat shock protein (Hsp) 70 is only repositioned and then up-regulated in susceptible snails with the normal parasite. This movement and change in gene expression seems to be controlled by the parasite. Other differences in the behaviour of genes support the view that some genes are responding to tissue damage, for example the ferritin genes move and are up-regulated whether the snails are either susceptible or resistant and upon exposure to either normal or attenuated parasite. This is the first time host genome reorganisation has been seen in a parasitic host and only the second time for any pathogen. We believe that the parasite elicits a spatio-epigenetic reorganisation of the host genome to induce favourable gene expression for itself and this might represent a fundamental mechanism present in the human host infected with schistosome cercariae as well as in other host-pathogen relationships.NIH and Sandler Borroughs Wellcome Travel Fellowshi

    Coronal radiation of a cusp of spun-up stars and the X-ray luminosity of Sgr A*

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    Chandra has detected optically thin, thermal X-ray emission with a size of ~1 arcsec and luminosity ~10^33 erg/s from the direction of the Galactic supermassive black hole (SMBH), Sgr A*. We suggest that a significant or even dominant fraction of this signal may be produced by several thousand late-type main-sequence stars that possibly hide in the central ~0.1 pc region of the Galaxy. As a result of tidal spin-ups caused by close encounters with other stars and stellar remnants, these stars should be rapidly rotating and hence have hot coronae, emitting copious amounts of X-ray emission with temperatures kT<~ a few keV. The Chandra data thus place an interesting upper limit on the space density of (currently unobservable) low-mass main-sequence stars near Sgr A*. This bound is close to and consistent with current constraints on the central stellar cusp provided by infrared observations. If coronally active stars do provide a significant fraction of the X-ray luminosity of Sgr A*, it should be variable on hourly and daily time scales due to giant flares occurring on different stars. Another consequence is that the quiescent X-ray luminosity and accretion rate of the SMBH are yet lower than believed before.Comment: 18 pages, 7 figures. Accepted to MNRA

    Response to comment on 'Amphibian fungal panzootic causes catastrophic and ongoing loss of biodiversity'

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    Lambert et al. question our retrospective and holistic epidemiological assessment of the role of chytridiomycosis in amphibian declines. Their alternative assessment is narrow and provides an incomplete evaluation of evidence. Adopting this approach limits understanding of infectious disease impacts and hampers conservation efforts. We reaffirm that our study provides unambiguous evidence that chytridiomycosis has affected at least 501 amphibian species

    A digital seismogram archive of nuclear explosion signals, recorded at the Borovoye Geophysical Observatory, Kazakhstan, from 1966 to 1999

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    Seismologists from Kazakhstan, Russia, and the United States have rescued the Soviet-era archive of nuclear explosion seismograms recorded at Borovoye in northern Kazakhstan during the period 1966–1996. The signals had been stored on about 8000 magnetic tapes, which were held at the recording observatory. After hundreds of man-years of work, these digital waveforms together with significant metadata are now available via the project URL, namely http://www.ldeo.columbia.edu/res/pi/Monitoring/Data/ as a modern open database, of use to diverse communities. Three different sets of recording systems were operated at Borovoye, each using several different seismometers and different gain levels. For some explosions, more than twenty different channels of data are available. A first data release, in 2001, contained numerous glitches and lacked many instrument responses, but could still be used for measuring accurate arrival times and for comparison of the strengths of different types of seismic waves. The project URL also links to our second major data release, for nuclear explosions in Eurasia recorded in Borovoye, in which the data have been deglitched, all instrument responses have been included, and recording systems are described in detail. This second dataset consists of more than 3700 waveforms (digital seismograms) from almost 500 nuclear explosions in Eurasia, many of them recorded at regional distances. It is important as a training set for the development and evaluation of seismological methods of discriminating between earthquakes and underground explosions, and can be used for assessment of three-dimensional models of the Earth’s interior structure

    Biomarker-indicated extent of oxidation of plant-derived organic carbon (OC) in relation to geomorphology in an arsenic contaminated Holocene aquifer, Cambodia

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    The poisoning of rural populations in South and Southeast Asia due to high groundwater arsenic concentrations is one of the world’s largest ongoing natural disasters. It is important to consider environmental processes related to the release of geogenic arsenic, including geomorphological and organic geochemical processes. Arsenic is released from sediments when iron-oxide minerals, onto which arsenic is adsorbed or incorporated, react with organic carbon (OC) and the OC is oxidised. In this study we build a new geomorphological framework for Kandal Province, a highly studied arsenic affected region of Cambodia, and tie this into wider regional environmental change throughout the Holocene. Analyses shows that the concentration of OC in the sediments is strongly inversely correlated to grainsize. Furthermore, the type of OC is also related to grain size with the clay containing mostly (immature) plant derived OC and sand containing mostly thermally mature derived OC. Finally, analyses indicate that within the plant derived OC relative oxidation is strongly grouped by stratigraphy with the older bound OC more oxidised than younger OC

    The Eighth Data Release of the Sloan Digital Sky Survey: First Data from SDSS-III

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    The Sloan Digital Sky Survey (SDSS) started a new phase in August 2008, with new instrumentation and new surveys focused on Galactic structure and chemical evolution, measurements of the baryon oscillation feature in the clustering of galaxies and the quasar Ly alpha forest, and a radial velocity search for planets around ~8000 stars. This paper describes the first data release of SDSS-III (and the eighth counting from the beginning of the SDSS). The release includes five-band imaging of roughly 5200 deg^2 in the Southern Galactic Cap, bringing the total footprint of the SDSS imaging to 14,555 deg^2, or over a third of the Celestial Sphere. All the imaging data have been reprocessed with an improved sky-subtraction algorithm and a final, self-consistent photometric recalibration and flat-field determination. This release also includes all data from the second phase of the Sloan Extension for Galactic Understanding and Evolution (SEGUE-2), consisting of spectroscopy of approximately 118,000 stars at both high and low Galactic latitudes. All the more than half a million stellar spectra obtained with the SDSS spectrograph have been reprocessed through an improved stellar parameters pipeline, which has better determination of metallicity for high metallicity stars.Comment: Astrophysical Journal Supplements, in press (minor updates from submitted version
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